New Agents Of SHIELD season 4,episode 3 official spoilers,synopsis released by ABC. Recently, ABC served up the new,official synopsis/spoilers for their upcoming “Marvel’s Agents Of SHIELD” episode 3 of season 4, and it sounds like it’ll feature some very dramatic and serious stuff as May is in great danger of becoming victim to her mysterious illness forever!

We’re also going to see Coulson, Fitz and Mack try to hunt down and stop a rogue group that’s looking to end inhuman Registration on a worldwide scale, and more! The episode is called, “Uprising.”

In the new episode 3 press release: As Coulson, Mack and Fitz attempt to track down and neutralize a rogue group looking to end Inhuman Registration worldwide, Simmons and Dr. Radcliffe will only have hours to save May before she succumbs forever to her mysterious illness.

Guest stars include: John Hannah as Holden Radcliffe, Natalia Cordova-Buckley as Elena “Yo-Yo” Rodriguez, Jason O’Mara as the Director, Gabriel Luna as Robbie Reyes, Mallory Jansen as Aida, Parminder Nagra as Senator Rota Nadeer, Alexander Wraith as Agent Anderson and Lorenzo James Henrie as Gabe Reyes.

Guest stars list number 2: Patrick Cavanaugh as Burrows, Ricky Saenz as pistol punk, Devon Libran as slugger punk, Valery Ortiz as Maria, Derek Hughes as The Amazing Mertz, Preston Flagg as Darryl, Stephanie Maura Sanchez as bridesmaid #1, Jen Kuo Sung as Chen, Dale Pavinski as Briggs, Michael Cory Davis as agitator, Aaron Gaffrey as mystery figure and Adriana Diaz as hostage.

The episode was written by Craig Titley, and Magnus Martens directed it. Episode 3 is scheduled to air on Tuesday night, October 11th at 9pm central time on ABC. Stay tuned.

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